- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Synthesis of New 3-(Pyrimidin-2-Yl Amino) Propane Hydrazide Derivatives | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 22, Issue 2, 2011, Pages 89-100 | ||
| Author | ||
| Nisreen K. Abood | ||
| Abstract | ||
| Condensation of 2-aminopyrimidin with methyl acrylate in acetic acid gave methyl 3-(pyrimidin -2-yl amino) propanoate compound (1) . Reaction of compound (1) with hydrazine hydrate resulted propanoyl hydrazide derivatives (2). Treatment of(2) with malic anhydride, phthalic anhydride ,succinic anhydride afforded pyridiazine derivatives (3-5)and then with acetylacetone, ethylacetoacetate, ethylcyanoacetate afforded a new derivatives pyrazole compound (6-8). Compound (2)react with different aldehydes or ketones gave new Schiff's bases derivatives(9-13) .Schiff,s bases converted into hetrocyclic compound by react with malic anhydride in dry benzene to gave oxazepine (14-18).The identification of isolated and purified compounds were elucidated by 1HNMR, IR,UV. | ||
|
Statistics Article View: 29 PDF Download: 10 |
||