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Synthesis Of New Nucleoside Analogue (6-Uracil-L-Ascorbic Acid) | ||
| journal of kerbala university | ||
| Article 1, Volume 1, Issue 0, 2005, Pages 154-161 PDF (0 K) | ||
| Authors | ||
| Majed Jari mohammed; Zeyad Kadhim Oleiwi | ||
| Abstract | ||
| In this research new nucleoside analogues of L-ascorbic acid was synthesized via protection of diol group of 5,6 positions of L-ascorbic acid by cyclic acetal formation, then protection of OH groups of 2,3 positions by benzoyl, after that deprptection of diol group to link tosyl group in 6 position of L-ascorbic acid by selective method then formation of nucleoside by the reaction with mercury salt of uracil that was synthesized previously by reaction of uracil with mercuric chloride in presence of ethanol as solvent. | ||
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