Study of the antimicrobial activity of silk sericin from silkworm bombyx mori

Nassif Jassim, Khalid; Jaffar Al-Saree, Omar

	Study of the antimicrobial activity of silk sericin from silkworm bombyx mori
IRAQI JOURNALOF COMMUNITY MEDICINE
Article 1, Volume 23, Issue 2, 2010, Pages 130-133
Authors
Khalid Nassif Jassim; Omar Jaffar Al-Saree
Abstract
Abstract Back ground: In this research, it is found that the natural silk sericin, the gummy substance that holds the fibroin stands in the silk filaments together which is produced by the silk worm Bombyx mori, has a good antimicrobial, antioxidant, and anti-tumor activity. Materials & Methods: this is achieved by Tensile strength and growing of spores colonies methods before and after treatment of the cotton fabric with 2% sericin solution and burying the treated samples in garden soil for 7 days to achieve the spores test (according to Iraqi standard 147/ 1990)(1). Results: The results showed that the spores colonies are reduced from (146) before treatment with sericin to (29) only after treatment. Also the Tensile strengths are increased about (5) times after treatment with 2% sericin. The micrococcus leuteus used to detect the effect of (10-20) mg/ml sericin to inhibit this kind of bacteria, by using a well diffusion method seeded nutrient agar, then incubated at (35-37) oC for 24 hours, zones of inhibition were observed between 9-12 mm in diameter. Conclusion: Results above indicate the presence of antimicrobial and antibacterial activity of silk sericin; it is possible to use the silk sericin for medical applications after isolation and identification of some pathogenic bacteria like Streptococcus pneumonia, Pseudomonas aeroginosa Escherichia coli to produce medical bandages, mouth wash, and antibacterial soaps & teeth paste. Key words: antimicrobial activity, silk sericin, bombyx mori
Keywords
antimicrobial activity; silk sericin; bombyx mori

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