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Adenosine Deaminase Activity in sera and lymphocytes of patients with Brucellosis | ||
| IRAQI JOURNALOF COMMUNITY MEDICINE | ||
| Article 1, Volume 19, Issue 2, 2006, Pages 181-183 | ||
| Authors | ||
| Mahmoood M Atia; Tahseen A Zydan; Ali M S Al-Doori; Wissam M Atia | ||
| Abstract | ||
| Abstract: Background: Adenosine deaminase enzyme has been used as marker for infectious diseases e.g. tuberculosis and AIDS. Its activity is found to be elevated in diseases in which there is a cell mediated immunity. This work was carried out to study adenosine deaminase activity in patients with brucellosis. Methods: Blood samples were collected from patients with brucellosis 35 samples before treatment and 30 after four days starting treatment) and 25 samples from apparently "healthy" controls. Adenosine deaminase was determined. Analysis of variance was used to examine the association of adenosine deaminase with infection. Results: Significant difference was noticed in adenosine deaminase enzyme between patients with infection and controls, and, also, patients after treatment. No such significant difference was observed in adenosine deaminase between patients after treatment and control. Conclusion: Adenosine deaminase activity was higher in patients with brucellosis. Further studies are needed to explain the causes and mechanisms of increased level of adenosine deaminase. Key word: Adenosine deaminase enzyme, Brucellosis, Iraq | ||
| Keywords | ||
| Adenosine deaminase enzyme; Brucellosis; Iraq | ||
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