- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Cytological Grading of Fine Needle Aspirates from Breast Carcinoma | ||
| IRAQI JOURNALOF COMMUNITY MEDICINE | ||
| Article 1, Volume 19, Issue 3, 2006, Pages 239-243 | ||
| Authors | ||
| Zainab A.J. AL-Obaidi; Raji H. AL-hadithi | ||
| Abstract | ||
| Abstract: Background: Breast carcinoma is the most common malignant tumor in females at the age group (15-74) years. Because neoadjuvant therapy including preoperative chemotherapy and tamoxifen is becoming increasingly common for treating early breast carcinoma, itُ s desirable to grade the tumor before surgery to select the appropriate treatment Aim of the study: 1-Grading the cytological material obtained by FNA performed on malignant breast lesions. 2-Assess the reliability of FNA by comparison with histopathology. Material & Method: One hundred and three malignant cases of breast lesions diagnosed by FNA were reviewed in Al-Kadhmiah Teaching Hospital from 1994-1998. Their histopathological confirmation was present in 91 cases only. Those aspirates were stained by H&E stain & were graded according to the Robinson grading system using six cytological parameters; cell dissociation, cell size, cell uniformity, nucleoli, nuclear margin & chromatin pattern and then grade them into three grades according to the total scores. Results: We were able to correctly correlate 74 cases (81.3%) of FNA cytological material graded according to the mentioned criteria with their histological grading for ductal carcinoma. For lobular carcinoma only histopathological confirmation was done. Performing Chi-square testX²=67.4 (p≤0.001). Conclusions: Cytological grade does not correspond exactly to histological grade but it is equally good if the variability in histological grade is considered due to tumor heterogeneity. Also the value of Robinson´s grading system in cytological grading since it is simple, take little time & the information obtained is of clinical use & may be of prognostic value especially when combined with mammographic findings. Key words: Breast carcinoma, FNA, grading. | ||
| Keywords | ||
| breast carcinoma; FNA; grading | ||
|
Statistics Article View: 101 PDF Download: 48 |
||