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Morphological development of the metanephric glomeruli in rat during peri-natal period | ||
| Iraqi Journal of Embryos and Infertility Researches | ||
| Article 1, Volume 1, Issue 2, 2011, Pages 9-12 | ||
| Abstract | ||
| background "The metanephric glomeruli develop from the metanephric blastema and ureteric bud. The nephron anlage undergoes multiple differentiation stages, fusion and invagination that lead to the formation of nephron. objective To describe the morphological changes and transformations that lead to formation of metanephric permanent glomerulus during peri-natal period. method The study was performed on albino rat as a model for mammalian embryonic development. Embryos of20-22 days of gestation and neonatal litters were investigated for renal development. The specimens were double fixed, plastic embedded and semi-thin sections stained with methylene blue were examined result it was shown that glomerular development oontinues during late pre-natal days and first week post-natally. Maturity was attended by the end of the 7lh post-natal day The developing glomerulus passes through the stages describes as vesicle, comma, S-shaped, double comma, elongation and ovale stage to become finally mature. conclusion The metanephric glomerulus passes through sequential, mufti-stage, pleomorphic development during peri-natal period. These features should be considered during evaluation of kidney during this period. | ||
| Keywords | ||
| metanephros; glomerulus; Development | ||
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