Helicobacter pylori and Glycemic Control in Iraqi Patien With Type 2 Diabetes

Fadil AL-Kazzaz, Fatin

	Helicobacter pylori and Glycemic Control in Iraqi Patien With Type 2 Diabetes
Al-Mustansiriyah Journal of Science
Article 1, Volume 24, Issue 2, 2013, Pages 57-68
Author
Fatin Fadil AL-Kazzaz
Abstract
Helicobacter pylori (H. pylori) is one of the most common cause of chronic bacterial infections in patients with gastrointestinal disorders in the world. Recent reports suggested that H. pylori might have high prevalence among patients with diabetes. The aim of the current study was to assess the prevalence rate of H. pylori infection and its effects on the control of glycemia in diabetic patients type 2. The authors enrolled 60 type 2 diabetic patients T2DM (29 male and 31 female) age between (35-75) years. A total of 30 healthy volunteers served as a control group was also included in the study.Groups were matched for gender and age and had similar geographical origin and socioeconomic status. Body mass index(BMI), fasting blood glucose & the percentage of blood level of glaciated Hemoglobin(HbA1C)were measured by Ion exchange chromatography, while the presence of H.pylori infection was demonstrated then determined its IgG antibody through the use ELISA technique. It was found that no statistically significant difference for H. pylori infection with BMI or age or gender &smoking history (p˃ 0.05) ,while there was a highly significant increase in fasting blood glucose or (HbA1c) levels or duration of DM among T2DM patients(P˂ 0.001). Indeed, infection with H. pylori is associated with type 2 diabetes mellitus with elevated levels of (HbA1c) and blood glucose highly significant , in patients with T2DM .More than fifty percent(51.42%) of the infected T2DM patients with H.pylori were overweight (BMI=25 -30kg/m).

Statistics Article View: 201 PDF Download: 105