- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Synthesis of New Chalcones and Pyrazoles Derived from Dehydroacetic Acid | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 24, Issue 2, 2013, Pages 79-88 | ||
| Author | ||
| Redha I. H. Al-Bayati | ||
| Abstract | ||
| This work involves the synthesis of chalcones from dehydro acetic acid. Four main chalcones were synthesized (1-4), also Chalcone (14) which synthesized from compound(6) and then the other derivatives (5, 6) were obtained from the reaction of compound (1) with hydrazine hydrate in the presence of formic acid and acetic acid respectively. Also, Pyrazole compounds (7-13) were synthesized through the reaction of chalcones with hydrazine or its substituents, while compounds (15, 16) have been synthesized by the reaction of DHA with ethyl P-amino benzoate and diethyl oxalate, respectively, in the presence of sodium ethoxide. Compound (17) was synthesized from the reaction of compound (15) with hydrazine, while compound (18) was obtained from the reaction of compound (16) with ortho phenylene diamine in the presence of acetic acid. The last two compounds (19-20) were synthesized from the cyclization of compound (1) with phenyl acetamide and ethyl acetoacetate, respectively. The structure of the synthesized derivatives were deduced by using some spectroscopic analysis such as UV, FT-IR and 1H-NMR | ||
|
Statistics Article View: 123 PDF Download: 65 |
||