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Determination of Anti-Müllerian hormone level in Polycystic Ovary Syndrome, Infertile, and Healthy Iraqi Women | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 24, Issue 3, 2013, Pages 1-12 | ||
| Author | ||
| Shatha M.J.AL-Khateeb | ||
| Abstract | ||
| Biochemical markers of ovarian reserve are needed in clinical practice for early detection of ovarian ageing or premature failure, and also to predict poor response to ovarian stimulation in assisted reproduction technologies. Despite limitations to predict pregnancy, anti-Mullerian hormone (AMH) is the most reliable single biochemical marker to predict ovarian response. The finding that AMH can be assessed at any day of menstrual cycle adds a great advantage to this marker over others that require a specific phase for assessment. Methods: A total of thirty six undiabetic female patients (17 infertile women and 19 with polycystic syndrome) their age ranged from 17-35 years old. Healthy controls (15) matched in sex and age were enrolled in this study for the determination of AMH concentration. Results : serum AMH concentration is significantly decrease in infertile women(P-value ˂ 0.05) when compared with healthy control, on the other hand there is significantly increase in the level of AMH concentration in women with polycystic ovary as compared with healthy control(P-value ˂ 0.05). Conclusion: Comparison of female AMH level with respect to average age is useful in fertility assessment, as it provides a guide to ovarian reserve and identifies women that may need to consider either egg freezing or trying for a pregnancy sooner rather than later if their long-term future fertility is poor | ||
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