Sialic Acid and Carcinoembryonic Antigen Level in  Type 2 Diabetes Mellitus

Hana,; Salman Yass, A

	Sialic Acid and Carcinoembryonic Antigen Level in Type 2 Diabetes Mellitus
Al-Mustansiriyah Journal of Science
Article 1, Volume 24, Issue 3, 2013, Pages 13-20
Authors
; a Salman Yass
Abstract
The purpose of the study was to find the association between serum sialic acid (SSA), carcinoembryonic antigen (CEA) levels and type 2 diabetes mellitus (T2DM). A total number of 75 patients with T2DM were taken from different regions of Baghdad city (included 47 females and 28 males). Those patients were selected by systematic random sampling and (25) samples were collected from apparently healthy individuals a control group (15 females and 10 males); with ages’ range of (35-75) years. This study was conducted by taking detailed historical background for each subject including sex, age, family history, smoking, and duration of DM. Serum sailic acid and CEA levels were estimated for both patients and control subjects, laboratory diagnosis depended on using enzyme-linked immunosorbent assay (ELISA) for SSA and CEA, while enzymatic and colorimetric method was used for glucose test in this study. The results of this study showed that most patients’ sera had increased SSA and CEA levels with significant differences in comparison with control group (P< 0.001). The mean of fasting blood glucose (FBG) for patients was (216.881±36.24 mg / dL) while it was (86.68±13.11 mg / dL) for control group. The mean of serum sialic acid levels in T2DM patients' sera was (81.21±9.00 mg /dL) compare with control group (65.12 ±3.32 mg / dL); while it was (1.73 ± 3.83ng /ml) for CEA among patients sera in comparison with (0.45 ± 0.39 ng / ml) for control group. The results of this study showed increased FBG, SSA and CEA levels with increment of age that refer to significant differences between patients

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