Antibiotic Sensitivity profile of bacteria isolated from wounds and skin infections

Taee,; M.S. Al, Orass

	Antibiotic Sensitivity profile of bacteria isolated from wounds and skin infections
Magazine of Al-Kufa University for Biology
Article 1, Volume 5, Issue 1, 2013, Pages 199-107
Authors
; Orass M.S. Al
Abstract
The choice of antibiotic is usually based on previously published susceptibility testing and previous s clinical success. Anaerobic bacteria are important because they dominate the diagnose flora. Some of these infections are serious and have high mortality rate. It has to be paid more attention to anaerobic infections because special precautions are needed for appropriate collection and transport of specimens.Aim of the study: To study the sensitivity profile of bacterial strains isolated from several types of infected skin and wounds toward several antibiotics. Methods: The study included 98 strains isolated from 150 patients with skin and wound infections patients hospitalized into Al-Diwanya teaching hospital from January 2009 to January 2010. A total of 150 samples were selected from patients with skin and wounds Infections including samples of burn wounds, cutaneous ulcer, surgical wounds, acnes and pustules . For the disc diffusion testing: ampicillin, gentamicin, amikacin, cefuroxime, cefoperazone, ciprofloxacin, piperacillin, Erythromycin, Cloxacillin, ceftriaxone, ceftazidime, Amoxicillin, Rifampin, Metronidazole, clindamycin, Ceftazidim, penicillinV, trimethoprim-sulfamethoxazol and amoxicillin _ clavulanic acid, disc were used. Results: In our research, we examined 150 specimens. Aerobic bacteria were recovered from 48 (32%) specimens, anaerobic bacteria only were recovered from 27 (18%) specimens, and mixed aerobic and anaerobic bacteria were recovered from 75 (50%) specimens. Ciprofloxacin was highly active drug that could eradicate the major pathogens bacteria from skin and wounds infection. Although metronidazole has relatively poor efficacy by itself, in combination with penicillin V the susceptibility of the bacteria in this study was virtually the same as amoxicillin. Conclusions: Ciprofloxacin seems to remain the antibiotic of choice because of its efficacy in polymicrobial infections, relatively narrow spectrum for bacteria found in skin and wounds infections, low toxicity , and low cost.
Keywords
antibiotic; Anaerobic bacteria; infected skin; wounds; burn wounds; cutaneous ulcer; surgical wounds; acnes and pustules

Statistics Article View: 159 PDF Download: 15