- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
The incidence of pan-drug resistance in a sample of Acinetobacter baumannii clinical isolates obtained from Al-Ramadi Teaching Hospital | ||
| IRAQI JOURNALOF COMMUNITY MEDICINE | ||
| Article 1, Volume 26, Issue 3, 2013, Pages 262-266 | ||
| Authors | ||
| Raya Muteea A. Nassar; Majid A. K. Lafi; Sammira M Salman | ||
| Abstract | ||
| Abstract Background: Acinetobacter infections have become more difficult to treat owing to the emergence of isolates resistant to all commonly prescribed antimicrobial drugs, particularly pan-drug resistant Acinetobacter baumannii. Aim of Study: to investigate the incidence of pan-drug resistance in a sample of A. baumannii clinical isolates obtained from Al-Ramadi Teaching Hospital Materials and Methods: Twenty-six A. baumannii were isolated from 130 wound and burn patients obtained from operative theatres and burn centre, in Al-Ramadi Teaching Hospital from October 2012 to May, 2011. Identifications were performed by standard microbiological techniques and by means of a commercial identification gallery (API 20E) and further confirmed by (API 20NE). The susceptibility of the isolates to selected major classes of anti-A. Baumannii agents were determined by the standard disk diffusion method as described in the guidelines of the Clinical Laboratory Standard Institute (CLSI). Appropriate tests were performed for detecting carbapenemase and metallo-β-lactamase production. Result: Out of 26 isolates of A. baumannii, 6/26 (23%) were imipenem-resistant pandrug resistant (IR-PDR) A. baumannii, i.e. resistant to all representative drugs of available anti-A. baumannii in Iraq. One out of 26 (4%) was imipenem-resistant multidrug resistant (IR-MDR). All the (7) imipenem-resistant A. baumannii isolates were obtained from the Burn Centre, six were isolated from patients have taken meropenem in their treatment and only one patient who had not taken meropenem but admitted to the centre at the same time with other two patients suffering from Steven-Johnson syndrome have been given meropenem, all showed positive results in the metallo-β-lactamase production screening tests. Conclusion: It is concluded that the presence of carbapenem, multidrug and pandrug resistance is evident in our sample of A. baumannii isolates and may be associated with the use of meropenem and inadequate infection control measures particularly in burn patients. Key words: Acinetobacter baumannii, Pan-drug resistance, Metallo-β-lactamase, Ramadi | ||
| Keywords | ||
| Acinetobacter baumannii; Pan; drug resistance; Metallo; lactamase; ramadi | ||
|
Statistics Article View: 111 PDF Download: 63 |
||