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Skeletal Metastasis;Distribution by Age, ,Sex,and Histological Classification(Medical city) | ||
| Iraqi Postgraduate Medical Journal | ||
| Article 1, Volume 12, Issue 2, 2013, Pages 192-195 PDF (0 K) | ||
| Author | ||
| Abdul Ridha Kh.Jabbar | ||
| Abstract | ||
| BACKGROUND: Skeleton is the one of the commonest sites of secondary cancer, it is seen more frequently than all primary bone tumors together. Vertebrae, pelvis and proximal parts of long bone are more involved by secondary metastasis. Breast cancer is the commonest cause of primary tumor followed by Prostatic carcinoma. Despite the advances in diagnosis but still about 10 % of cases remain as secondary with undetermined primary site. OBJECTIVE: To disclose the distribution of bone metastasis and their primary site among Iraqi patients. PATIENTS AND METHOD: 102 patient were enrolled in a retrospective study conducted in medical city complex in Baghdad/ Iraq from January 1990- July 2000. Patient are either known to have primary malignant tumor and discovered to have secondary metastasis to bone as part of the routine screen or development of symptoms suggestive of bone metastasis, the other group of patients are presented with bone metastasis. All patients are subjected to intensive medical history and proved their secondary metastasis by excisional biopsy or fine needle aspiration with histopathological diagnosis RESULTS: The mean age of our patients was 41 years, with range (2-80 years), men were commonly involved than women, the peak incidence of metastasis was in 1991. Vertebral bodies are commonly involved and lungs are the most common primary site CONCLUSION: Well differentiated columnar adenocarcinoma is the commonest histopathological type of malignant tumor metastases to bones, lungs are the most common primary site. Undetermined primary tumors are still consist a diagnostic problem in our daily practice more cooperative team work is needed to disclose the final diagnosis | ||
| Keywords | ||
| bone metastasis; Adenocarcinoma; osteolytic | ||
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