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Study of Glutathione and Total thiol Levels in Irritable Bowel Syndrome Patients | ||
| Journal of University of Babylon | ||
| Article 1, Volume 20, Issue 2, 2012, Pages 601-604 | ||
| Author | ||
| Lamia A. M. Al-Mashhedy | ||
| Abstract | ||
| Background: Irritable bowel syndrome (IBS) is a common gastrointestinal condition characterized by abdominal pain and cramps; changes in bowel movements (diarrhea, constipation, or both); gassiness; bloating; nausea; and other symptoms. There is no cure for IBS; however, dietary changes, stress management, and sometimes medications are often able to eliminate or substantially reduce its symptoms. Purpose: It is well do documented that disturbances of oxidant-antioxidant balance in psycho-somatic disease especially in irritable bowel syndrome. Materials and Methods: Glutathione and total thiols were studied in twenty patients aged 18-35 years, compared with twenty sex and age matched healthy subjects. Results: Serum glutathione and total thiol groups levels were significantly decreased in irritable bowel syndrome(IBS) than healthy controls. | ||
| Keywords | ||
| KEYWORDS; Glutathione GSH; Total thiols SH | ||
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