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Positive Serological markers associated with Infertility. Across sectional study on 50 couples | ||
| Journal of University of Babylon | ||
| Article 1, Volume 20, Issue 3, 2012, Pages 931-941 | ||
| Author | ||
| Areej-A- Jabbar | ||
| Abstract | ||
| Background The current prevalence of medical contact infertility varies from (3.6%-17%) of other infertility causes.(Shmidt et al: 1995).Natural infection by a variety of organisms have been linked to pregnancy loss and infertility, including Toxoplasma gondii, Viruses such as Rubella, Cytomegalo virus and Herpes simplex virus(William et al: 1998). Patients and Methods: A cross sectional study was carried out during the first 6 months of 2009 for 50 infertile couples, the sample members were assessed clinically and investigated for their infertility state. A blood sample was collected for serological detection of specific Toxoplasma, Rubella, Cytomegalo virus and Herpes simplex virus IgG and IgM anti bodies .The results were statistically analyzed against the age (in years),the type, the cause, the duration of infertility and the history of Hepatitis in each. Results: Toxoplasmosis found among 3 wives (3.6%) and one (2%) husbands, but was shared in one couple only out of 50 couples of the sample (2%).Rubella virus was found in 18 (36%) of wives and 19 (38%) husbands also shared in 16 couples (32%) of the sample. Cytomegalo virus found to be positive in18 wives (36%) and in 16(32%) husbands, shared in 14 couples (28%) of the sample while Herpes simplex virus was positive in 6 wives (12%) and 5(10%) husbands but shared in4 couples(8%). The eldest wives and the youngest husbands had higher association with the positive (TORCH) serological markers (100%), (66.7%) respectively, also the primary infertile wives and the secondary infertile husbands shared high association with positive serological markers, (59.1%). and both wives and husbands with duration of infertility (2-5) years had higher association with positive markers (76%) and (57.7%) respectively .The history of previous Hepatitis in both wives and husbands had similar association (100%) with positive serological markers, and all the results were statistically non significant. Conclusion: The positive serological findings in infertile couples are important factors to assess, that can high light to the fact that infertility has a multiple correlating factors including serological markers and Medical causes, enhancing to arrange more researches in future with increasing sample size and variables. | ||
| Keywords | ||
| infertility; TORCH test for Toxoplasma gondii; Rubella virus; Cytomegalo virus; and Herpes simplex virus | ||
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