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Synthesis and biological studies for some heterocyclic compounds derived from 2-Morpholino-1,8- naphthyridine-4-carboxylic acid | ||
| Baghdad Science Journal | ||
| Article 1, Volume 10, Issue 3, 2013, Pages 758-765 | ||
| Author | ||
| Ala I. Ayoob | ||
| Abstract | ||
| New heterocyclic compounds derived from 2-Morpholino-1,8-naphthyridine-4-carboxylic acid such as oxadiazolo, thiadiazolo – thione and triazolo-thione have been prepared and characterized on the basis of IR and 1H NMR spectra data. The hydrizide compound was utilized as a starting material for preparing of these compounds. The second part of this study involves the biological studies of some of these naphthyridine derivatives by using three different kinds of bacteria namely: Staphylococcus aureus, Pseudomonas aeruglnosa and Escherichia coli. The data indicated that some of these compounds have a good activity against the tested bacteria in comparison to antibiotics. | ||
| Keywords | ||
| Key Words; Biological; heterocyclic compounds; Morpholino; naphthyridine; Carboxylic acid | ||
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