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Osteopetrosis Manifesting As a Femoral Fracture in Childhood: A Case Report | ||
| Kerbala Journal of Medicine | ||
| Article 16, Volume 4, Issue 9, 2011, Pages 1033-1038 PDF (0 K) | ||
| Author | ||
| Mahdi Abdul Sahib | ||
| Abstract | ||
| osteopetrosis is a genetically determined bone disease that develops as a result of malfunction of osteoclastic activity leading to excessive deposition of immature bone, thickening of cortical bones and narrowing of the medullary cavities. The condition is rare; the overall incidence is estimated to be 2-10 per million populations. We report a 9-years old child with osteopetrosis presented as pathological femoral fracture. The clinical characteristics together with the negative family history, radiological findings of generalized osteosclerosis and laboratory results (mild anemia) suggest that our patient probably fits in to the intermediate autosomal recessive group of osteopetrosis. Management presents a unique technical challenge in these patients because it often resulted in complications including blunting or breakage of drill bits, intraoperative fractures, delayed healing, nonunion and postoperative infections. This report highlights for technical difficulties during surgery and, hence, prolonged operative time; therefore, preoperative planning is mandatory in the management of fracture in osteopetrotic bone. | ||
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