Study of Serum Leptin and Lipid Profile Concentration in Psoriatic Patients in Hilla - Iraq

K. Al-Hattab, Mohammed; E. Al-Gazally, Moaed; A. Al-Asadi, Radwan

	Study of Serum Leptin and Lipid Profile Concentration in Psoriatic Patients in Hilla - Iraq
Kerbala Journal of Medicine
Article 1, Volume 4, Issue 10, 2011, Pages 1109-1116 PDF (0 K)
Authors
Mohammed K. Al-Hattab; Moaed E. Al-Gazally; Radwan A. Al-Asadi
Abstract
background: To study the role of biochemical markers in sera of psoriatic patients. Aim: Evaluation and study of the correlation between lipid profiles and Leptin in sera of psoriatic patients in Hilla province – Iraq. Patients and Methods: The study was conducted on sixty psoriatic patients and thirty apparently healthy persons were taken as control group. Blood collected from the clinic of dermatology in Merjan Teaching Hospital and from the consultative center for allergy and asthma in Hilla city / Iraq. Sera obtained from the blood were used to determine the effect of psoriasis on leptin, total cholesterol, high density lipoprotein (HDL-C), triglycerides (TGs), very low density lipoprotein (VLDL), and low density lipoprotein cholesterol (LDL-C) concentration. Results and Discussion: The results of the present study showed (significant increase in leptin, total cholesterol, triglycerides, very low density lipoprotein and low density lipoprotein cholesterol concentration), significant decrease in high density lipoprotein cholesterol in sera of psoriasis group compared to control group, significant increase in leptin concentration in sera of psoriasis females than males, significant increase in leptin concentration in sera of psoriasis patients as increase BMI (body mass index).

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