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Rhinocerebral Mucormycosis | ||
| Kerbala Journal of Medicine | ||
| Article 1, Volume 1, Issue 0, 2007, Pages 8-16 PDF (0 K) | ||
| Author | ||
| Karim Q.AL.Naffi | ||
| Abstract | ||
| Rhinocereberal mucormycosis is a relatively rare opportunistic fungal infection, usually affect patient with DM, renal failure, organ transplant, desferal user&rarely in healthy person5, 7, 8,9,18. We try to look how frequent this disease is prevalent in the cases admitted to our hospital & what is the outcome of our treatment. Method A prospective study done in Al-Hussein General Hospital-Karbala/Iraq in the period June 2001-Augest 2005, to examine all patients with DM, CRF who have unexplained headache, facial edema, ophthalamoplgia or disturbed conscious for rhinocerebral mucormycosis.Diagnosis based on clinical suspicion , The presence of necrotic tissues in nasal cavity, radiological exam including CT- scan whenever available &fungal detection on of nasal swab &scraping.. Result We diagnosed ten patients. Eight treated surgically &with amphotricin B (0.5mg/kg/d for six weeks). Two were treated with amphotricin B&local cleaning only. Seven of those treated patients were cured; three died, those who died were presented late with ophthalamoplegia with or without disturbed conscious. Conclusion Rhinocereberal mucormycosis which is relatively rare disease actually is present in our patients especially those who have DM with or without renal failure or patient with CRF on dialysis3.13.16. It is a killing disease yet if we carry high index of suspicion in those cases who is presented with headache, dirty nasal discharge, fever &facial edema. We can diagnose them earlier &start treatment to control of the underlying condition, with aggressive surgical interventions combined with amphotricin B, we may safe many patients life. | ||
| Keywords | ||
| Rhinocereberal; mucormycosis; fungus; diabetes; chronic renal failure | ||
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