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Study of Some Cytokines and Hormones in a Sample of Iraqi women with Polycystic ovarian syndrome and Their Relation to Obesity. | ||
| Al-Mustansiriyah Journal for Pharmaceutical Sciences | ||
| Article 1, Volume 13, Issue 2, 2013, Pages 58-64 | ||
| Authors | ||
| Huda J. Waheed; Perry H. Saifallah; Isam N. Salman | ||
| Abstract | ||
| Abstract: The present study aimed to measure serum vaspin and apelin levels in women with PCOS to show their rule in the pathogenesis of PCOS. Ninety eight women with PCOS, 51 non-obese [body mass index (BMI) less than 25 kg/m2] and 47 obese (BMI >25 kg/m2) were enrolled in the study. Each group is compared to apparently healthy women as a control group matched for age and BMI. Clinical history, anthropometric measurements and biochemical and hormonal analysis were determined. The mean serum level of vaspin and apelin showed statistically significant difference between PCOS patients (non-obese and obese) compared to control women (non-obese and obese) respectively. Also, the levels of both parameters (vaspin, apelin)showed significant differences between PCOS obese patients and non-obese ones. It is concluded that serum vaspin and apelin level increased in PCOS women particularly the obese. These data suggest their involvement in the pathogenesis of PCOS Key word: Polycystic ovary syndrome, vaspin, apelin. | ||
| Keywords | ||
| Key Word; vaspin; apelin | ||
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