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Relationship Between Conductivity Of Erythrocytes Suspension And Some Variable After And Before Treatment With New And Used Antioxidants For Rabbits With Induced Diabetic | ||
| Journal of University of Babylon | ||
| Article 1, Volume 21, Issue 4, 2013, Pages 1239-1243 | ||
| Authors | ||
| Eyman H. Al-Rikabi; Oda M. Al- Zamely | ||
| Abstract | ||
| Diabetes mellitus (DM) is associated with hyperglycemia and oxidative stress. Oxidative stress which indicates the imbalance between reactive oxygen species (ROS) and defensive antioxidants system. In this work we study the relation between the conductivity of washing solution of erythrocyte membrane with induced diabetic rabbits (n=3) compare with rabbits control (n=3)after and before treatment with following antioxidants aspirin (n=3) ,GSH(n=3) ,Vitamin C (n=3) and with new derivative 4(1,2-di hydro -4,6-dihydroxy pyrimidine -2- yH thio)-3-hydroxy-5-(2,2-dimethyl-1,3-dioxolan-4-yl) furan-2(5H)one (3A) which believed as antioxidants, The results shows the conductivity of washing solution of erythrocyte membrane in diabetic rabbits a significant increased(p<0.000) as compare with control group and a significant decreased in treatment groups with aspirin, GSH, Vit C, and 4(1,2-di hydro -4,6-dihydroxy pyrimidine -2- yH thio)-3-hydroxy-5-(2,2-dimethyl-1,3-dioxolan-4-yl) furan-2(5H)one . | ||
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