Study The Cellular, Humoral Immune Response And The Prevalence Of Enteric Adenovirus, Rotavirus and Norovirus Causing Diarrhea In Infants

F. Al-Rubaei, Abeer

	Study The Cellular, Humoral Immune Response And The Prevalence Of Enteric Adenovirus, Rotavirus and Norovirus Causing Diarrhea In Infants
Journal of University of Babylon
Article 1, Volume 21, Issue 5, 2013, Pages 1633-1640
Author
Abeer F. Al-Rubaei
Abstract
In this research many different viruses that may cause gastroenteritis had been studied, including Rotaviruses, Noroviruses, Adenoviruses, type 40 or 41, Sapoviruses, and Astroviruses. The main symptoms of viral gastroenteritis are watery diarrhea and vomiting. In this study we used Rapid chromatography immunoassay for the qualitative detection of Rotavirus and Adenovirus in human feces specimens , enzyme sorbent immuno assay technique for detection Norovirus. this study included 100 blood and feces specimens. (80) for infected patient that lies in (16) specimens was acute infantile diarrhea with Norovirus infection and 11 specimens was Acute infantile diarrhea with adenovirus infection , (20) specimens was Rotavirus, (33) specimens was Acute infantile diarrhea without Norovirus, Adenovirus and Rotavirus infection and (20) specimens as a control group . Distribution of Acute infantile diarrhea with Norovirus, Adenovirus , Rotavirus and control group according to the type of feeding. In the breast feeding were 37.5%, 18.18%,35%,45.45%,50% respectively but it were 62.5%, 81.82%,65%,54.55%, 50 % in Mixed feeding respectively. The statical analysis was high significant P<0.05 in Mixed feeding in comparing with Breast feeding. The study shows that the infant (7-12)month have high percentage of infected with virus . The level of non specific immune response by using differential leukocytes counts [DLC] was studied also. The statical analysis of percentage of Neutrophils, Lymphocytes and Monocytes was lower significant in Acute infantile diarrhea with Norovirus, Adenovirus and Rotavirus and Acute infantile diarrhea in comparing with control group. and high significant P<0.05 the average level of immunoglobulin G [IgG]of Acute infantile diarrhea comparing with control group .

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