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Immunological study of patients with asthma | ||
| Journal of University of Babylon | ||
| Article 1, Volume 21, Issue 7, 2013, Pages 2400-2407 | ||
| Author | ||
| Alaa J.H. and Thanaa A.M | ||
| Abstract | ||
| An immunological study were performed to estimation the concentrations of immunoglobulin IgE , IL-4 , IL-13 and PGE2 by ELISA , calculate the total and differential WBCs counts of patients with asthma , as well as the relationship between this disease and gender in Babylon province . The study reveals that the IgE and IL – 4 levels were significantly increased (p<0.05) in patients (second and third age categories ) compared with healthy subject . The results illustrated that the patients show a significant elevation in IL – 13 levels in first (p<0.01) , second (p<0.05) and third (p<0.01) age categories respectively compared with control group ;furthermore, the study revealed that the concentration of prostaglandin –E2 (PGE2) show highly significant elevation (p<0.05) in patients compared with healthy individuals . The results displays that there is no significant differences (p<0.05) in total WBCs count between patients and control group , and the same results was in means of neutrophils , lymphocytes and monocytes ; while there were significantly increased (p<0.05) in eosinophils (first and second groups ) and basophils (all groups) in patients compared with healthy subject ,furthermore, the results reveals increased ratio of disease in females compared with males . | ||
| Keywords | ||
| An immunological study were performed to estimation the concentrations of immunoglobulin IgE; and PGE; calculate the total and differential WBCs counts of patients with asthma; as well as the relationship between this disease and gender in Babylon province; The study reveals that the IgE and IL; in patients; The results illustrated that the patients show a significant elevation in IL; second; and third; age categories respectively compared with control group; furthermore; the study revealed that the concentration of prostaglandin; in patients compared with healthy individuals; The results displays that there is no significant differences; in total WBCs count between patients and control group; and the same results was in means of neutrophils; lymphocytes and monocytes; while there were significantly increased; in eosinophils; the results reveals increased ratio of disease in females compared with males | ||
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