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The Effects of Organophosphorus Insecticides on Liver of Male Mice | ||
| Journal of University of Babylon | ||
| Article 1, Volume 21, Issue 7, 2013, Pages 2420-2424 | ||
| Authors | ||
| Khalid H. Gathwan; Nada K. Al-hussaini; Qasim M. Ali Al-Ameri; Mona N. Al-Terehi; Liqaa Yehya Al-Gebory; Ali H. Al-saadi | ||
| Abstract | ||
| Background: Pesticides cause ecological problems which may result in immediate mass mortality and biological magnifications.Objectives: To study the effect of organophosphorus on liver of male mice.Material and Methods: Male Balb/c mice weighing 30-35 gm, 60 days old, were treated orally with monocrotophos(1/3 LD50,1.8 mg/kg bw) and methyl parathion (1/3 LD50 ,2.8 mg/kg bw) for 30 days. The liver weight, and aminotransferase, acid phosphatase and alkaline phosphatase in homogenates were estimated.Results: The present study revealed the levels of acid phosphatase, alkaline phosphatase, aspartate aminotransferases and alanine aminotransferases, were significantly (p<0.05) increased in liver with all of the two organophosphates.Conclusion: It has been concluded that (monocrotophos and methyl parathion) caused increased in the levels of phosphatase and aminotransferase as well as decreased in liver weight. | ||
| Keywords | ||
| Monocrotophos; mice; Phosphatase; Aminotransferase | ||
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