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Synthesis of new 9H-Carbazole derivatives | ||
| Iraqi Journal of Science | ||
| Article 1, Volume 54, Issue 5, 2013, Pages 983-993 | ||
| Authors | ||
| Nahed M.Alsoultany; Ahmed W. Naser; Suad M. Alaraji | ||
| Abstract | ||
| The aim of the present work is to synthesis of new 9-ethyl carbazole derivatives .The 3-acetyl-9-ethyl carbazole was achieved by the reaction of compound (1) with acetyl chloride in the presence of aluminum chloride to give compound (2). Reaction of compound (2) with a ppropriate aromatic aldehyde yielded 3-(3-Phenyl -1-Oxy propen-1-yl)9-Ethyl carbazole(3a-3h).The reaction of (3) with hydrazine hydrate gave 3-(5-aryl-4, 5-Dihydro-3-pyrozolyl)9-Ethyl carbazole(4a-4h). Also compound (3) reacted with phenyl hydrazine gave 3-(1-phenyl-5-aryl-4-pyrozoline-3-yl)9-Ethyl carbazole (5a-5h). The reaction of compound (3) with guanidine carbonate in presence of NaOH (40%) gave the 3-(2-amino-6-aryl-4-pyrimidinyl)9-Ethyl carbazole (6a-6h). The prepared compounds were conformed by TLC, FT-IR and some of them 1H-NMR. | ||
| Keywords | ||
| Carbazole; guanidine; pyrozoline derivatives; pyrimidinyl derivatives | ||
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