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Pharmacokinetics And Bioavailability Of Ibuprofen Tablets Produced by AKRKHIN Company (Russia) In Comparison With Ibuprofen Tablets Produced by BOOTS Company (Brufen Tablets, England). | ||
| Al-Rafidain University College For Sciences | ||
| Article 1, Volume 0, Issue 32, 2017, Pages 309-324 | ||
| Author | ||
| Jaefer Hashim Muhsin | ||
| Abstract | ||
| Ten healthy male adult volunteers aged 20-40 years and of weight 55-75 kgm administered in empty stomach and in two occasions under same conditions 200 mg of ibuprofen tablets produced by AKRKHIN company (Russia) and 200 mg of ibuprofen tablets produced by BOOTS company (England). Statistical comparison of the pharmacokinetic parameters including the absorption half-life, the elimination half-life, the time to reach maximum concentration of the drug in serum and the maximum concentration of the drug in serum between the above companies indicated insignificant differences. Moreover it appeared that ibuprofen tablets produced by AKRKHIN company (Russia) is bioequivalent to the ibuprofen tablets produced by BOOTS company (England). | ||
| Keywords | ||
| Pharmacokinetics | ||
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