Study of immunological and epidemiological of Toxoplasmosis in aborted women in fallujah city

S. Ismail, Mohammed; Sh. Daoud, Ibrahim; Wahab B. Hussein, Abdul

	Study of immunological and epidemiological of Toxoplasmosis in aborted women in fallujah city
Tikrit Journal of Pure Science
Article 1, Volume 18, Issue 2, 2013, Pages 34-42
Authors
Mohammed S. Ismail; Ibrahim Sh. Daoud; Abdul Wahab B. Hussein
Abstract
The study included collection of 80 blood samples from aborted women , aged between 16-54 years attended the general Fallujah hospital for the prevalence of the parasite Toxoplasma gondii in Fallujah city-AL-Anbar province by two methods: direct latex agglutination (LAT) and Enzyme linked immunosorbent assay (ELISA) and measurement of antibodies concentration of IgM, IgG, IgE, IgA, Complements C3, C4, some immunological features of cells The results showed that the percentage of total infection in accordance with age groups in the study (16-25),(26-35),(36-45) by LAT were 43.75%, 40.90%, 46.15% 42.11% respectively and with ELISA test 32.50%, 31.82%, 35.90%, 32.50% respectively, the percentage of total, acute infection by ELISA-IgM in accordance with age groups were 10%, 13.64%, 12.82%, 0% whereas total, chronic infection by ELISA-IgG were 22.50%, 18.18%, 23.08%, 26.31% respectively. The measurement of antibodies levels of IgG, IgM, IgE by ELISA, IgA and complements C3, C4 by single radial immuno diffusion showed a significant increase in the average antibodies levels of specific IgM, IgG against T. gondii whereas no significant increase in the average antibody level of IgE, IgA and complement C3,C4 in the aborted women in comparison to control . The infection with T. gondii showed significant difference in the activity of Polymorphonuclear neutrophils (PMNs) in the phagocytosis of candida yeast and reduction of Nitroblue tetrazolium, whereas little effect on viability of PMNs isolated from aborted women of all age groups in comparison to control .

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