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Effect of aquatic and alcohol extracts Citrus aurantifolia fruit on some Physiological and Biochemical parameters in blood of males albino rats | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 18, Issue 2, 2013, Pages 133-140 | ||
| Author | ||
| Adnan mohammed Ahmeed Al-Dolemy | ||
| Abstract | ||
| The study carried out to investigate the effect of orally providing for eight days from each Citrus aurantifolia fruit aquatic and alcoholic extracts at 25, 50 and 100mg/g concentration of animal body weight on some physiological and biochemical parameters in male rats. The results showed asignificant increase (p≤ 0.05) in Total Leucocyte (WBC) , Mean Corpuscular Hemoglobin Concetration (MCHC), with increasing concentration of extract , and increasing in Hemoglobin (Hb), Red Blood Corpuscular Count (RBC), Packed Cell Volume (PCV), Monocyte, Neutrophil, Eosinophil Count, HDL-C, at 50 and 100 mg/g concentration. Also the a significantly decreased in cholesterol, triglycerides, LDL-C, VLDL-C, Glucose, Urea, and activity of ALT, AST and AP. Whereas it did not show significant in the Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Lymphocyte, and Albumin, with the increased concentration of extract. Also it did not shows significant in total protein and globulin at 25, 50 concentration, but increased at concentration 100, in aquatic extract , When compared with the same values in control group. The alcoholic extract showed same values of aquatic extract except asignificant increasing obtained in Monocyte, Neutrophil, Lymphocyte. It did not show significant in Hb, RBC, PCV, Eosinophil, total protein and globulin, with increasing concentration of extract. When compared with aprovided value of control group Dimethyl Sulfoxide (DMSO) alone. The study conclution is the Citrus aurantifolia fruit aqueous and alcoholic extracts improved the blood and biochemical changes of albino male rats. | ||
| Keywords | ||
| Citrus aurantifolia; aquatic and alcoholic extracts; physiological biochemical; parameters | ||
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