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Effect of herbs mixture composed of Nigella sativa ,Trigonella-foenum graceum ,Cyperus rotundus ,Teucrium polium on the level of glutathione malondialdehyde ,urea and proteins of blood serum in diabetic patients type 2 | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 18, Issue 2, 2013, Pages 141-150 | ||
| Authors | ||
| Nahida Saieed Hamoodi Al-Chalabi; Reem Nawaf Hamdon Al-Swaaf | ||
| Abstract | ||
| This study included estimation of some biochemical parameters, antioxidants and lipid peroxidation in the serum of diabetic patients type 2, who are treated with polyherbal mixture containing (Nigella sativa, Trigonella Foenum gracum, Cyperus rotundus, Teucrium polium) and effect of this mixture in patients to knowing the relationship of the following parameters (Total protein, albumin, globulin, urea, Alkaline phosphatase ALP,Glutathione GSH and Malondialdehyde MDA).Samples of (70) diabetic patients type 2 were taken including (44) samples for group one who used herbs and chemical treatment (drugs) ,(26) samples for group two who are used herbs only. These groups were compared with (60) samples obtained from healthy persons as a control group. The results were shown that there is an increase the value of the following parameters (ALP, MDA) in the serum diabetic patients then the results decreased after treatment of these patients with polyherbs mixture for one, two, and three months in both groups. On the other hand, the results showed a significant increase of free radicals during the measurement of malondioldehyde level and a decrease of antioxidants such as glutathione of diabetic type 2 patients compared to the control group (Healthy persons) . At the same time, the results were shown a decrease in total protein, albumin and glutathione values before treatment of these patients with a polyherbs mixture but an increasing in these values after treatment whereas, decreasing was observed at stopping of the treatment with these polyherbs mixture. At the same time also, the result were indicated no significant was present for the concentration of urea before and after treatment in three months one, two and three . | ||
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