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Nephrotoxicity effect of Cannabis sativa (Marijuana) plant on the male albino rats. | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 18, Issue 3, 2013, Pages 16-19 | ||
| Author | ||
| Lana Sardar Salih Al-Alem | ||
| Abstract | ||
| The objective of this study was to investigate the effects of cannabis (marijuana) induced toxicity in kidney tissue. Thirty mature male rats of six to 8-week-old male rats were divided into three groups, ten animals in each group. Group 1, served as control and received standard diet and tap water (ad libitium), while animals of second group injected intrapretoneously with 1ml of the solution (5mg/1kg) body weight, while the animals of third group injected intrapretoneously with 1ml of the solution (10mg/1kg) body weight. Histological examination of rats kidney treated, with cannabis showed many lesions characterized by coagulative necrosis in epithelium lining proximal convoluted tubules some of glommeruli revealed bowman's capsules dilatation and other showed a trophy or loss of glommeruli. | ||
| Keywords | ||
| Cannabis; cannabinoids; marijuana; histopathology; kidney | ||
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