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Study the effect of medicinal plants mixture ( Boswellia carterii , Trigonella foenum graecum, Lupinus termis , Vitis vinifera seeds ) on the metabolic equilibrium in patients with type II diabetes mellitus | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 18, Issue 4, 2013, Pages 9-20 | ||
| Authors | ||
| Nahida Saieed Al-Chalabi; Shihab Ahmad Al-Bajari | ||
| Abstract | ||
| In this research study the effect of plants mixture (Boswellia carterii ,Trigonella foenum graecum, Lupinus termis , Vitis vinifera seeds) with metformin or daonil drugs or both on (50) case for a long time type II diabetic mellitus patients . Also (40) case for the model type II diabetic mellitus patients (without chemical drug), . As well as (100) case for health person as control group . The patients were administrated by a plants mixture as capsules two times daily . Then the patients were followed for three months and then a month after stopping it . The fasting blood was collected at every month , and then stored the serum at – 20 C˚. This study included determination of some biochemical parameters (Glucose, Total cholesterol, HDL-c., LDL-c., TG., uric acid, urea, creatinine, total protein, albumin, GOT., GPT., MDA), and determination of enzymatic (GPx., GST., SOD., and Cp) and non-enzymatic (GSH., vitamin A , E ,and C) antioxidants . Also estimation the activity of aldol reductase enzyme was done , as well as estimation insulin hormone level and insulin resistance . The results show that treatment with herbs lead to a significant decrease in Glucose , Total cholesterol , VDL-c., LDL-c., TG., creatinine , GOT., MDA l in the model type II diabetic mellitus patients and also a significant decrease in Glucose, creatinine , MDA in the long time type II diabetic mellitus patients especially when combination with both daonil and metformin were used , also a significant increase in non-enzymatic(GSH., vitamin C , E) and enzymatic (GPx) antioxidant levels for two groups of patients . | ||
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