background: Rheumatoid arthritis affects women more than men 3:1. Rheumatoid
arthritis can start at any age but most commonly occurs in the 30 – 50 age groups.
Rheumatoid arthritis also has oral, occular manifestations, dryness, swelling of
salivary glands, xerostomia, oral and mucosal ulcerations. The aims of this study were to
determine the oral manifestations in newly and old (previously) diagnosed Rheumatoid
arthritis patients and compare it with healthy controls (without systemic diseases) and finally
to find the accurate prevalence of these manifestations in rheumatoid arthritis patients.
Materials and methods: Seventy two (72) subjects were incorporated in this study, they
were divided into 2 groups, Rheumatoid arthritis patients group: fifty – two (52) patients with
rheumatoid arthritis, they were (11) males and (41) females, Seventeen newly diagnosed
rheumatoid arthritis untreated patients. Thirty five rheumatoid arthritis patients were on
methotrexate treatment. All rheumatoid arthritis patients were without any other systemic
disease. Healthy control group: - twenty healthy control subjects with no signs and symptoms
of any systemic disease. They were sex and age matched to rheumatoid arthritis patients.
Results: The results revealed that the main oral manifestations of Rheumatoid arthritis
patients were angular cheilitis, candidial infection, tempromandibular joint disorder, oral
ulceration, and xerostomia. In old diagnosed rheumatoid arthritis patients, the percentages of
oral ulcerations, tempromanbdibular joints, and xerostomia was significantly higher than in
newly diagnosed rheumatoid arthritis patients. While the percentage of angular chilitis and
candidial infections in newly diagnosed rheumatoid arthritis patients was significantly higher
than in old (previously) diagnosed patients.
Conclusion: Rheumatoid arthritis is a chronic disease in which Saliva is a good
recommended sample for evaluation and estimation of the severity of disease as well as
treatment follow up. Oral ulceration and xerostomia are the most prominent oral
manifestations coincide with the progress of the disease and treatment. |