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Inhibitory Effect of Cranberry Fruit Extracts on Adhesion of Urinary Tract Infection Bacteria | ||
| Journal of Al-Nahrain University - Science | ||
| Article 1, Volume 16, Issue 4, 2013, Pages 182-187 | ||
| Author | ||
| Rita N. N. Rammo | ||
| Abstract | ||
| In vitro adhesion of bacteria to uroepithelial cells in the presence of cranberry methanol and water base extracts has been studied. Microorganisms taken from patients with urinary infections were (48%) Escherichia coli, (26%) Klebsiella pneumoniae, (16%) Proteus mirabilis, and (10%) Staphylococcus aureus. The adhesion of bacteria to uroepithelial cells in the presence of cranberry methanol base extract with varying concentrations showed high inhibition at concentrated extract (25 mg/ml) with S. aureus and E. coli being mostly affected and to a lesser extent with P. mirabilis and K. pneumoniae. Inclusion of water in the extraction of cranberry, showed an inhibition effect of the concentrated extract (25 mg/ml) as being ca. 22% less effective than the methanol base extract. Results are discussed in terms of bacterial structure and the disruption of binding between the receptors of uroepitheilal cells. | ||
| Keywords | ||
| Cranberry extract; Bacterial adhesion; Uuroepithelial cells; Urinary Tract Infection | ||
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