- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
The role of urinary 5- Hydroxyindoleacetic acid determination in diagnosis of acute appendicitis | ||
| Tikret Journal of Pharmaceutical Sciences | ||
| Article 1, Volume 9, Issue 2, 2013, Pages 305-311 | ||
| Authors | ||
| Hamid Hindi Sarhan; Amina Hamed Alobaidi | ||
| Abstract | ||
| Background: Appendicitis is associated with high rate of wrong diagnosis. Objective. To evaluate the predictive value of 5-HIAA in diagnosis of appendicitis. Patients & Methods: Spot urine samples were collected from 147 patients with appendicitis and 45 healthy control. 5-HIAA was detected in urine samples in all patients using ELISA method. Results: The mean 5-HIAA level was 4.5 umol/mmol creatinine in healthy individuals, 5.8 umol/mmol creatinine in wrongly diagnosed appendicitis, and 15.7 umol/mmol creatinine in patients with appendicitis. The difference between patients group with appendicitis and other 2 groups was statistically highly significant [P<0.001], However, the difference between the normal individuals group and wrongly diagnosed group was statistically non significant. The test had 81% sensitivity and 85 specificity. Conclusion: This study indicated that determination of 5-HIAA as non- invasive test was with predictive value in diagnosis of appendicitis. Thus reducing the malpractice in surgical operation in Iraqi community. | ||
| Keywords | ||
| HIAA; acute appendicitis; diagnosis | ||
|
Statistics Article View: 124 PDF Download: 3 |
||