Effect of Ginger on the activity of some antioxidant enzymes (Superoxide dismutase, and Catalase) of Alloxan Experimental Induced-Diabetic Rabbits

EntedharRiffatSarhat,

	Effect of Ginger on the activity of some antioxidant enzymes (Superoxide dismutase, and Catalase) of Alloxan Experimental Induced-Diabetic Rabbits
Al-Mustansiriyah Journal of Science
Article 1, Volume 22, Issue 5, 2011, Pages 192-200
Author

Abstract
Oxidative stress is considered as one of the important consequences of poor glycemic control. This study was designed to explore the possible clinical utility of ginger as a antioxidant enzymes. This study was performed on alloxan induced diabetic rabbits with age of (6,12) month's. The selected rabbits were allocated into four groups each include 10 rabbits. The first group was healthy rabbits as compared with second group. The second diabetic without treatment as control group with the last three groups. The third and forth group diabetic treated with extract 250mg/Kg, and 500mg/Kg of body weight respectively as a single daily dose for 6 weeks. The elevation procedure was base on the measurement of the level of(Superoxide dismutase (SOD),Catalase(CAT), and blood sugar.Analysis of data revealed significant, dose dependent effects of ginger on the antioxidant enzyme, SOD,and CAT were significantly elevated, while blood glucose were significantly reduced, associated with significant improvement in glycemic control.

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