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Effect of crude extract of Date palm pith Phoenix dactylifera cultivar. Zahdi on growth of cancer cell lines | ||
| Iraqi Journal of Cancer and Medical Genetics | ||
| Article 1, Volume 6, Issue 2, 2013, Pages 159-164 | ||
| Authors | ||
| Bedir M.Al-Azawi; Nahi Y. Yaseen; Aminah M.Alneaemy | ||
| Abstract | ||
| This work represented a preliminary study of the effect of aquous crude extract of date palm pith (Phoenix dactylifera cultivar. Zahdi) on the growing of two cancer cell lines(Human Rabdomyosarcoma –RD) , (Glioblastoma-ANG) in vitro. different concentrations of extracts (1250,2500,5000,10000) μg / ml were taken and it´s effectiveness in inhibiting the growth of cancer cells was tested in different exposure periods are (24,48, 72) hour . The results showed that, there is fatal cytotoxic effect of extract and this effect was dependent on the concentration, It is noticed that the cytotoxic effect increased according to concentration . The concentration 10000 µg/ml gave higher growth inhibition to RD , were ( 90.7 ) % compaired with control 100% after 24 hours from exposure time , and compaired with other concenterations which gave lower growth inhibition .while inhibition gowth of ANG was( 82.9)% by 10000 µg/ml for 24 hours. When exposure time increase to 72 hours the percentage of growth inhibition for cell lines (ANG,RD) was (67 ,88.8) respectively.This result showed that aquous crude extract of date palm pith have acytotoxic effect on the growing of the two cell lines (RD ,ANG) In vitro. | ||
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