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Leptin and Related Biochemical Parameters in Obese Osteoarthritis | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 22, Issue 5, 2011, Pages 128-140 | ||
| Author | ||
| Eman Saadi Saleh | ||
| Abstract | ||
| Osteoarthritis (OA) is a joint disorder characterized by progressive deterioration of articular cartilage. Obesity (OB) is one of many factors that participate in developing OA. Most obese (ob) subjects have high leptin (L) level suggesting “leptin resistance” as a mechanism of OB in this condition. Other biochemical parameter in addition to L are lipid profile (LP) including cholesterol (C), triglycerides(TG), lipoprotein(Lp) such as high &low density lipoproteins (HDL,LDL) that play an important role in OB. In this study eighty individuals were selected, divided into four groups twenty in each group.The age ranged from (45 to 55) years with mean value ± standard mean of error(52.34±2.12). Group (A): OB+ OA. Group (B): OB. Group (C): OA. Group (D): Neither OB nor OA as control (c). This study shows an elevation in L, LP except HDL serum level in obese osteoarthritis (OOA) whose their body mass index (BMI) more than (30) measured by weight in kilograms per height square meters (Kg/m2). | ||
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