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Preparation of Poly [N- Aryl Sulfonamide Maleimide Derivatives] | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 22, Issue 5, 2011, Pages 157-171 | ||
| Author | ||
| Firyal M.A | ||
| Abstract | ||
| In thiswork N- arylsulfonamidesmaleimides and their corresponding polymers were prepared from reaction of maleimide as N-sodium salt with chloro sulfonic acid, then reacted with aryl amines, the new N- sulfonamide maleimides were polymerized by free radical using Azobisisobuteronitrile at 70 ºC with dioxane as a solvent.The physical properties of all prepared polymers were studied and characterized by FTIR and UV. spectroscopy.These new- sulfonamide polymers were exhibit drugs properties as antibiotics after treating bacterial infections due to containing the (-SO2NH)and imide groups.Thermogravimetricanalyses of the prepared polymers were measured, and swelling %was studied. and controlled release of ampicillin drug polymer was studied in{PH=7.4}at 37 0C. some of the prepared polymers are antibacterial agents to overcome shortcomings which is critically important. | ||
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