Correlation Between Interleukins 1 α,6 and Echocardiographic Results in Patients with Heart Failure

Khazal Abed Chabuk, Shahlaa; Saheb Al-Momen, Amer; F. Alsamaraee, Israa

	Correlation Between Interleukins 1 α,6 and Echocardiographic Results in Patients with Heart Failure
Journal of University of Babylon
Article 1, Volume 22, Issue 4, 2014, Pages 1442-1451
Authors
Shahlaa Khazal Abed chabuk; Amer Saheb Al-Momen; Israa F. Alsamaraee
Abstract
Background: Difference in echocardiographic results between normal heart subjects and heart failure patients Heart failure is the inability of the heart to supply blood flow and therefore oxygen delivery to peripheral tissues and organs..The cytokines like IL-1 may play a significant role in the pathogenesis of several forms of myocardial dysfunction. Our aim was to investigate the correlation between Interleukins 1,6 and echocardiographic results in heart failure patients and comparison of the echocardiographic results of heart failure patients with those of normal subjects group. The cytokine profile and Echocardiographic results in patient with heart failure (n=80) age 62.35.7 years was compared with that of age matched healthy individuals (n=20) age of 59.76.3 years. Blood sample was taken from both control and patients groups for interleukine-1 , 6 measurement by ELISA Kit (Ray Bio). There is significant difference in echocardiographic values between healthy subjects and heart failure patients. A negative and positive linear correlations was found between Interleukin 1, 6 and echocardiographic parameters. In control group, the mean of interleukin-1- is (1.21.4) pg/ml and those in patients with heart failure was (6.089.32) pg/ml. There is significant increase in Interleukin-1-, 6 in patients with heart failure.

Statistics Article View: 248 PDF Download: 21