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Evaluation of Serum levels of INF-γ and IL-12 in patients with chronic hepatitis B | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 22, Issue 4, 2011, Pages 39-48 | ||
| Author | ||
| Muhammed A. Al-Dabagh | ||
| Abstract | ||
| The specific cellular immune response play a main role in the hepatic necrosis that occur with hepatitis B virus (HBV) infection and in the persistence or lack of viral infection. The aim of this study was to evaluate the cellular immune response in patients with chronic hepatitis B virus (CHBV) infection, via estimation of serum levels of interferon-gamma (IFN-γ) and interleukin-12 (IL-12),. Venus blood samples were collected from 45 patients with CHBV infection. Other 20 blood samples were collected from healthy individuals as control group. Enzyme linked immune sorbent assay (ELISA) was used to estimate the serum levels of (IFN-γ) and (IL-12). The results showed insignificant drooping in serum levels of IFN-γ and IL-12 respectively in CHBV patients group as compared with healthy control group. | ||
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