Evaluation of different methods for LDL_Cholesterol measurement in Iraqi adult population.

K. Chlimeran, Saba

	Evaluation of different methods for LDL_Cholesterol measurement in Iraqi adult population.
Medical Journal of Tikrit
Article 1, Volume 19, Issue 2, 2013, Pages 208-220
Author
Saba K. Chlimeran
Abstract
Objective: To evaluate the association of baseline LDL-C concentration as determined by a direct assay with those calculated using friedwald equation in a group of healthy lraqi population. Subjects and methods: The study was conducted in Mosul city in northern lraq, from October 2009-April 2010.fasting venous blood sample were obtained from all subject involved in the survey, by anticubital venepuncture between 8.00 a.m and 10.00 a.m. Serum lipid profile was measured for all subjects following 12 hours fasting, this profile include total cholesterol, triglyceride, HDL cholesterol ,LDL cholesterol (Friedewald formula),and direct LDL cholesterol. All the biochemical analyses were performed in the clinical chemistry laboratory of the department of biochemistry, collage of medicine, university of Mosul, lraq. Result: There was no significant difference between Friedwald formula LDL-C and direct LDL-C. There was a positive correlation between Friedwald formula and direct immunoinhibition (IIH)methods, and The was a positive correlation between LDL-C and HDL-C. Conclusion: The direct assay in this study correlated highly with Friedewald calculation but was 5-10mg/dl the lower LDL-C concentration by direct method, so we can use Friedewald calculation that its less expensive than direct LDL-cholesterol.

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