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EFFECT OF PURE LIGNAN FROM FLAXSEEDS (LINUM USITATISSIMUM) ON INDUCED AND ANTIMUTAGENIC ON BACTERIAL SYSTEM | ||
| Iraqi Journal of Biotechnology | ||
| Article 1, Volume 9, Issue 3, 2010, Pages 564-577 | ||
| Abstract | ||
| The study aimed to compare pure lignan compound with methotraxete (MTX) drug on three bacterial isolates (Bacillus ssp-.(G3), Arthrobacter spp-(G12) and Brevibacterium spp. (G27)). In addition, mutagen (MTX) was compared a standard mutagen which called (NTG). The mutagen MTX has higher mutation effect than NTG on the bacterial isolates. The lignan compound showed no effect at 50 and 75 g/ml concentrations but at 100 g/ml of lignan was caused the mutagen resistance to streptomycin for treated isolates 383.3, 166.6 and 166.6 mutation/ml for G3 , G12 and G3 isolates respectively. This means the lignan concentrations have the inhibition effect on bacterial isolates which result in dead ratio ranged between 1.9– 54 % on the G3 isolates. | ||
| Keywords | ||
| Lignan; Methotraxete; Bacterial isolates; Mutagen resistance | ||
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