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Interleukin-1α Level among Iraqi patients with Acute Leukemia | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 19, Issue 1, 2008, Pages 1-8 | ||
| Author | ||
| Batool A. Al-Haidary | ||
| Abstract | ||
| Leukemia is a malignant disease (cancer) of the bone marrow and blood. It is characterized by the uncontrolled accumulation of blood cells. Leukemia is divided into four categories: Myelogenous or Lymphocytic, each of which can be acute or chronic. Forty Iraqi Acute Leukemic patients’ samples included 22 Acute Myelogenous Leukemia (AML) and 18 Acute Lymphoblastic Leukemia (ALL) have been estimated for IL-1α using ELISA technique in comparison with 25 apparently healthy controls. This study reveals that there is a highly significant elevation in the level of this cytokine among ALL patients’ samples in comparison with control group (P< 0.001) for both AML and ALL group. Moreover there is no significant difference in IL-1α level before and after treatment (P> 0.05). In conclusion there is an effect for acute leukemia on IL-1α level particularly among AML cases in which it began to decline after treatment though it is non-significantly. | ||
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