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Evaluation the immune suppressive effect of aflatoxin B1 in mice | ||
| journal of kerbala university | ||
| Article 1, Volume 7, Issue 3, 2011, Pages 1-6 PDF (0 K) | ||
| Abstract | ||
| Aflatoxin B1 cause immune suppression especially in cellular immunity and decrease the number of T and B cells .The percentage of both CD4+ and CD8+ Tcells which are, in general, used as markers for helper and cytotoxic T cells ,are affected by aflatoxin B1 and showed lower percentage when injected with aflatoxin B1 four successive doses in mice for 16 days ( CD4+Tcell =224.25 , CD8+Tcell =177) and eight successive doses for 32 days ( CD4+Tcell =159 , CD8+Tcell =144) when compared with the untreated mice (control group) (CD4+Tcell =361 , CD8+Tcell=237.5)for 16 days and (CD4+Tcell =338.33 , CD8+Tcell=257)for 32 days | ||
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