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Possible Role for Interleukin-5 in Asthma | ||
| Journal of the Faculty of Medicine | ||
| Article 1, Volume 48, Issue 4, 2006, Pages 425-430 | ||
| Authors | ||
| a E. Jasim; ; Batool A. Al-Haidary; Yacoob Y. Al-Rubaeyi | ||
| Abstract | ||
| Background: Asthma is an allergic disease characterized by airway obstruction as a result of cellular accumulation due to the liberation of certain mediators. Among those mediators are the cytokines such as IL-5.Patients & Methods: Interleukin-5 concentration has been estimated in 94 sera samples of Asthmatic patients in comparison with 41 non-asthmatic bronchitis as patient controls in addition to 30 apparent healthy control group using ELISA method.Results & Conclusions: There is highly significant elevation of IL-5 in the asthmatic cases in comparison with healthy controls (P< 0.001). We conclude that this cytokine may play the major role in asthmatic attack & it may be a good marker for the disease. | ||
| Keywords | ||
| Asthma; bronchitis; Eosinophilia | ||
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