Effect of phenolic compoundsof leaves extracts from Mentha longifolia and Mentha spicata on somebiochemical parameters of female rats

G. Al-Fartosi, Khalid; A. Al-Rekabi, Eman

	Effect of phenolic compoundsof leaves extracts from Mentha longifolia and Mentha spicata on somebiochemical parameters of female rats
Journal of College of Education for Pure Science
Article 1, Volume 4, Issue 1, 2014, Pages 309-315
Authors
Khalid G. Al-Fartosi; Eman A. Al-Rekabi
Abstract
The objective of this study was performed toextract the phenolic compounds from Mentha longifoliaand Mentha spicata, and to shed a light on their activity against oxidant- antioxidant status and their effect on lipid profile in female rats. Two doses (200 and 400 mg/kg) from each plant were used and the animals were injected intraperitonially for 30 days as one dose/day. The results showed a significant decrease in the MDA and CP of the female rats treated with phenolic extracts of M. longifolia at dose (200-400) mg/kg and phenolic extracts of M. spicata at dose 200 mg/kg, and a significant decrease in the serum level of cholesterol and TG of the female rats treated with phenolic extracts ofM. longifolia at dose (200-400) mg/kg and phenolic extracts of M. spicata at dose 200 mg/kg, and The results showed a significant increase in the HDL and a significant decrease in the LDL with phenolic extracts of M. longifolia at dose (200-400) mg/kg when compared with control group, which treated with normal saline. While the female rats treated with phenolic extracts of M. longifolia and M. spicata at dose (200,400) mg/kg showed non significantdecrease in plasma VLDL, when compared with control group.
Keywords
Mentha spicata; Mentha longifolia; phenolic compounds; MDA; HDL; LDL; VLDL

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