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Androgenic –Anabolic Steroids Abusing Effect on Liver Enzymes and Lipid Profile in Male and Female Rats | ||
| Journal of College of Education for Pure Science | ||
| Article 1, Volume 4, Issue 2, 2014, Pages 191-204 | ||
| Authors | ||
| Nehaya M. Al-Aubody; Mohammad A. AL-Diwan | ||
| Abstract | ||
| The present study was conducted at Veterinary Medicine College–University of Basrha /Iraq to investigate the effect of testosterone( Sustanon ® 250) abusing on some physiological and biochemical parameters. Sixty four male and female rats were divided into four groups(each group consisted of 8 males and 8 females). The first group served as control group in which the rats dosed by intramuscular injection with 10 μ l olive oil weekly for 12 weeks, the rest 3 treated groups (G1 . G2 and G3) in which the rats dosed by intramuscular injection with 50 . 100 and 150 mg Sustanon ® 250 / kg B.W. respectively weekly for 12 weeks , then all rats were terminated for the physiological and biochemical tests . The Sustanon ® 250 through its effect on liver caused increasing both ALT and AST and decreasing the ALP in treated rats compared with control group . The lipid profile was significantly affected by Sustanon ® 250 injection through elevation of TG and VLDL , but lowering the HDL ,LDL and AI. | ||
| Keywords | ||
| Androgenic; Liver Enzymes; lipid profile | ||
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