Study of effect alcoholic extract of Piper nigrum L.plant seeds on some hematological and biochemical parameters of albino rats.

Mohamed AL- Khazali, Ennas

	Study of effect alcoholic extract of Piper nigrum L.plant seeds on some hematological and biochemical parameters of albino rats.
journal of al-qadisiyah for pure science(quarterly)
Article 1, Volume 13, Issue 3, 2013, Pages 68-76 PDF (0 K)
Author
Ennas Mohamed AL- Khazali
Abstract
The current study included using the ethanolic extract of piper nigrum seeds for knowing itʼs effect in some heamatological and biochemical parameters of of the albino rats .this study used 24 adult rat,aged 3 menthes ,it has been distributed them randomly on four equal groups ,numbers each groups composed of 6 rats ,these animals groups treated as following : control group C given drinking water only ,the first treated group T1 given ethanolic extract of Piper nigrum seeds with concentration of 25 mg/kg ,the second treated group T2 given alcoholic extract with concentration of 50mg/kg and T3 group given alcoholic extract at dose 100mg/kg,after finishing this test amounting 60 days counting the blood from the heart directly for study of some hematological parameters such as RBC,WBC, Hb, PCV and some biochemical parameters included total protein concentration ,total cholesterol TC concentration, high density lipoprotein cholesterol HDL-C and low density of lipoprotein cholesterol LDL-C ,the results showed significant increase P <0.05 in RBC,HB, PCV,HDL-C and total protein while no significant changed in WBC of the treated animals compared with control animals and the results showed significant decrease P<0.05 in level of total cholesterol and LDL-C in the treated groups compared with control group. therefore, this study refers to positive effects for alcoholic extact of Piper nigrum seeds on hematological and biochemical parameters of albino rats.

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