Objectives: To investigate the association of viral infections present in the lower genital tract of males and relationship with male infertility.
Methods: ELISA technique of 175 semen and serum specimens, collected over 12 months from males investigated for infertility, were retrospectively assessed.
Results: One hundred and seventy five seminal fluid, blood and serum specimens from men investigated for infertility over a period of 1 year from February 2011 to February 2012 were analyzed. The seminal fluids and serum of patients mentioned to the laboratory from the fertility clinics of Babylon maternity and children Hospital and outer clinics. The results had shown that from 284 viral infection there were, rubella consist 20.6%, Herpes simplex I 22.9% , Herpes simplex II 55.4% , Cytomegalovirus 33.1% , Human papilloma virus 15.4% , Adeno-associated virus 10.8% , Epstein-Barr virus 4%.
Also the infection with viruses revealed that it is higher in azoospermic+oligospermic patients than normospermic group (control) as shown in table 2 and figure2. We revealed in this study that azoospermic and oligospermic patients formed the highest ratio of the viral infections. there is 88.9% rubella infection, 90% Herpes simplex I, 83.5% Herpes simplex II, 76.2% Cytomegalovirus, 77.7% Human papilloma virus, 100% Adeno-associated virus, 85.7% Epstein-Barr virus in azoospermic and oligospermic compare with normospermic patients which are 11.1%, 10%, 16.5, 13.8%, 22.3%, 0%, 14.3% respectively.
Conclusions: using sensitive procedures for assays, we detected an unexpectedly high prevalence of sexually transmitted pathogens in semen from asymptomatic infertility patients. |