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Controlled Release of Vitamin (C) From Acrylamide Grafted Chitosan Hydrogel | ||
| Al-Mustansiriyah Journal of Science | ||
| Article 1, Volume 21, Issue 5, 2010, Pages 123-133 | ||
| Author | ||
| Ahmed Jasim | ||
| Abstract | ||
| Chitosan was modified through chemical grafted of acrylamide on the Chitosan polymer by free radical copolymerization in the presence of potassium persulfate as initiator. Various of grafting percentages have been obtained by changing the concentration of monomer (acrylamide). The percentage of grafting increases with the increasing of monomer concentration. The prepared polymers have been characterized by IR spectroscopy to identify the structure of the grafted polymer. The gelation of modified polymers (acrylamide grafted chitosan) according to the equilibrium swelling degree has been investigated in two different media (distilled water and n-saline). Acrylamide grafted chitosan shows high uptake of water, suggests its hydrophilicity. In vitro controlled release of vitamin (C) from hydrogel of prepared polymers was studied in two different media (distilled water and n-saline) using ultra violate absorption to follow quantities released at different times. The concentrations of vitamin (C) released increased gradually and then attain affixed value. | ||
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